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Article

Mouse polyQ database: a new online resource for research using mouse models of neurodegenerative diseases.

Molecular brain - 29 Oct 2015

Szlachcic Wojciech J, Switonski Pawel M, Kurkowiak Małgorzata, Wiatr Kalina, Figiel Maciej

Abstract excerpt

BACKGROUND: The polyglutamine (polyQ) family of disorders comprises 9 genetic diseases, including several types of ataxia and Huntington disease. Approximately two decades of investigation and the creation of more than 130 mouse models of polyQ disorders have revealed many similarities between these diseases. The disorders share common mutation types, neurological characteristics and certain aspects of...

Topics

Animals
Databases, Protein
Disease Models, Animal
Internet
Mice
Neurodegenerative Diseases
Peptides
Phenotype
Research
Search Engine
User-Computer Interface

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26515641
DOI: 10.1186/s13041-015-0160-8
PMCID: PMC4625465

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