Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HOXD9 promotes epithelial-mesenchymal transition and cancer metastasis by ZEB1 regulation in hepatocellular carcinoma.

Journal of experimental & clinical cancer research : CR - 29 Oct 2015

Lv Xiupeng, Li Linlin, Lv Li, Qu Xiaotong, Jin Shi, Li Kejun, Deng Xiaoqin, Cheng Lei, He Hui, Dong Lei

Abstract excerpt

Hepatocellular carcinoma (HCC) is a common malignant tumor that severely threatens human health. The poor prognosis of HCC is mainly attributed to intrahepatic and extrahepatic metastases. HOXD9 proteins belong to a superfamily that regulates the development and control of many cellular processes, including proliferation, apoptosis, cell shape, and cell migration. HOXD9 can also function as an oncogene in several...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Hepatocellular
Share to Epithelial-Mesenchymal Transition

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heterografts

Share to Homeodomain Proteins

Share to Liver Neoplasms

Share to Neoplasm Metastasis

Share to Neoplasm Proteins

Share to Zinc Finger E-box-Binding Homeobox 1

Source

Open in PubMed Open full text

Identifiers

PMID: 26514226
DOI: 10.1186/s13046-015-0245-3
PMCID: PMC4625617

Genes

HOXD9
ZEB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HOXD9 promotes epithelial-mesenchymal transition and cancer metastasis by ZEB1 regulation in hepatocellular carcinoma.PMID 26514226Read ↗

ZEB1 promotes tumorigenesis and metastasis in hepatocellular carcinoma by regulating the expression of vimentinSemantic proximity Read ↗

ETS1 is coexpressed with ZEB2 and mediates ZEB2‐induced epithelial‐mesenchymal transition in human tumorsSemantic proximity Read ↗

HOXB9 Overexpression Promotes Colorectal Cancer Progression and Is Associated with Worse Survival in Liver Resection Patients for Colorectal Liver Metastases.Semantic proximity Read ↗

Homeobox B9 promotes the invasion and metastasis of hepatocellular carcinoma cells via the EZH2–MIR203A–SNAI2 axisSemantic proximity Read ↗

Bromodomain-containing protein 9 promotes hepatocellular carcinoma progression via activating the Wnt/β-catenin signaling pathwaySemantic proximity Read ↗

RHBDD1 promotes colorectal cancer metastasis through the Wnt signaling pathway and its downstream target ZEB1.Semantic proximity Read ↗

MEF2D Transduces Microenvironment Stimuli to ZEB1 to Promote Epithelial–Mesenchymal Transition and Metastasis in Colorectal CancerSemantic proximity Read ↗

Bioinformatics Analysis and Insights for The Role of COMMD7 in Hepatocellular CarcinomaSemantic proximity Read ↗

Bioinformatics Analysis and Insights for the Role of COMMD7 in Hepatocellular CarcinomaSemantic proximity Read ↗

HOXA9 transcription factor is a double-edged sword: from development to cancer progressionSemantic proximity Read ↗

HOXB4/METTL7B cascade mediates malignant phenotypes of hepatocellular carcinoma through TKT m6A modification.Semantic proximity Read ↗

BRD4 promotes tumor growth and epithelial-mesenchymal transition in hepatocellular carcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.