Article
MicroRNA 17-5p regulates autophagy in<i>Mycobacterium tuberculosis</i>-infected macrophages by targeting Mcl-1 and STAT3
29 Oct 2015
Abstract excerpt
Autophagy plays a crucial role in the control of bacterial burden during Mycobacterium tuberculosis infection. MicroRNAs (miRNAs) are small non-coding RNAs that regulate immune signalling and inflammation in response to challenge by pathogens. Appreciating the potential of host-directed therapies designed to control autophagy during mycobacterial infection, we focused on the role of miRNAs in regulating M....
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