Article
HIV-1 Adapts To Replicate in Cells Expressing Common Marmoset APOBEC3G and BST2.
Journal of virology - 15 Jan 2016
Fernández-Oliva Alberto, Finzi Andrés, Haim Hillel, Menéndez-Arias Luis, Sodroski Joseph, Pacheco Beatriz
Abstract excerpt
UNLABELLED: Previous studies have shown that a major block to HIV-1 replication in common marmosets operates at the level of viral entry and that this block can be overcome by adaptation of the virus in tissue-cultured cells. However, our current studies indicate that HIV-1 encounters additional postentry blocks in common marmoset peripheral blood mononuclear cells. Here, we show that the common marmoset APOBEC3G...
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