Article
Comparable actions of omalizumab on mast cells and basophils.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Jan 2016
Serrano-Candelas E, Martinez-Aranguren R, Valero A, Bartra J, Gastaminza G, Goikoetxea M J, Martín M, Ferrer M
Abstract excerpt
BACKGROUND: Omalizumab (OmAb) has recently been approved for the treatment of diseases other than allergic asthma, including chronic urticaria. The exploration of the use of OmAb in chronic urticaria was based on the presence of IgE autoantibodies against autoantigens such as anti-IgE, anti-FcεRI, and IgE antibodies against thyroid peroxidase in certain patients with chronic urticaria. OmAb recognizes and...
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