Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MicroRNA-223 Is Upregulated in Active Tuberculosis Patients and Inhibits Apoptosis of Macrophages by Targeting FOXO3

27 Oct 2015

Abstract excerpt

BACKGROUND: Macrophage apoptosis is a host innate defense mechanism against tuberculosis (TB). AIM: In this study, we aimed to investigate the role of microRNA-223 (miR-223) in macrophage apoptosis of TB. METHODS: We analyzed apoptosis in peripheral blood macrophages of active TB patients, infected human macrophages (TDMs and MDMs) with the Mycobacterium tuberculosis (Mtb) strain H37Rv, and observed the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Mechanisms and Therapy
Share to FOXO transcription factor regulation
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26505221
DOI: 10.1089/gtmb.2015.0090

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MicroRNA-223 Is Upregulated in Active Tuberculosis Patients and Inhibits Apoptosis of Macrophages by Targeting FOXO3PMID 26505221Read ↗

miR-155 is upregulated in patients with active tuberculosis and inhibits apoptosis of monocytes by targeting FOXO3Semantic proximity Read ↗

Role of apoptosis and autophagy in tuberculosisSemantic proximity Read ↗

MicroRNA-325-3p Facilitates Immune Escape of Mycobacterium tuberculosis through Targeting LNX1 via NEK6 Accumulation to Promote Anti-Apoptotic STAT3 SignalingSemantic proximity Read ↗

MicroRNA-142-3p inhibits autophagy and promotes intracellular survival of Mycobacterium tuberculosis by targeting ATG16L1 and ATG4cSemantic proximity Read ↗

CircAGFG1modulates autophagy and apoptosis of macrophages infected by Mycobacterium tuberculosis via the Notch signaling pathwaySemantic proximity Read ↗

Macrophage Apoptosis in TuberculosisSemantic proximity Read ↗

miRNAs in immune responses to Mycobacterium tuberculosis infection.Semantic proximity Read ↗

RIP3 impedes Mycobacterium tuberculosis survival and promotes p62-mediated autophagySemantic proximity Read ↗

FOXO3 Transcription Factor Regulates IL-10 Expression in Mycobacteria-Infected Macrophages, Tuning Their Polarization and the Subsequent Adaptive Immune ResponseSemantic proximity Read ↗

The Transcriptional Foundations of Sp110-mediated Macrophage (RAW264.7) Resistance to Mycobacterium tuberculosis H37RaSemantic proximity Read ↗

Mycobacterium tuberculosis Lipoprotein MPT83 Induces Apoptosis of Infected Macrophages by Activating the TLR2/p38/COX-2 Signaling PathwaySemantic proximity Read ↗

Increased autophagy activity regulated by LC3B gene promoter DNA methylation is associated with progression to active pulmonary tuberculosis diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.