Article
Genome-wide evolutionary and functional analysis of the Equine Repetitive Element 1: an insertion in the myostatin promoter affects gene expression.
BMC genetics - 26 Oct 2015
Santagostino Marco, Khoriauli Lela, Gamba Riccardo, Bonuglia Margherita, Klipstein Ori, Piras Francesca M, Vella Francesco, Russo Alessandra, Badiale Claudia, Mazzagatti Alice, Raimondi Elena, Nergadze Solomon G, Giulotto Elena
Abstract excerpt
BACKGROUND: In mammals, an important source of genomic variation is insertion polymorphism of retrotransposons. These may acquire a functional role when inserted inside genes or in their proximity. The aim of this work was to carry out a genome wide analysis of ERE1 retrotransposons in the horse and to analyze insertion polymorphism in relation to evolution and function. The effect of an ERE1 insertion in the...
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