Article
Sequence analysis of myostatin promoter in cattle.
Cytogenetic and genome research - 1 Jan 2003
Crisà A, Marchitelli C, Savarese M C, Valentini A
Abstract excerpt
Myostatin (GDF8) acts as a negative regulator of muscle growth. Mutations in the gene are responsible for the double muscling phenotype in several European cattle breeds. Here we describe the sequence of the upstream 5' region of the myostatin gene. The sequence analysis was carried out on three animals of nine European cattle breeds, with the aim to search for polymorphisms. A T/A polymorphism at -371 and a G/C...
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