Article
Subacute hepatic necrosis mimicking veno-occlusive disease in a patient with HFE H63D homozygosity after allogeneic hematopoietic cell transplantation with busulfan conditioning.
International journal of hematology - 1 Dec 2015
Chen Sylvia, Osborn James Dane, Chen Xinjian, Boyer Michael W, McDonald George B, Hildebrandt Gerhard Carl
Abstract excerpt
Busulfan is a commonly used chemotherapeutic agent in myeloablative conditioning regimens for allogeneic hematopoietic cell transplantation (allo-HCT). It has been associated with sinusoidal-obstructive syndrome(SOS) as a life-threatening complication of myeloablative allo-HCT, yet it has not been found to cause severe hepatocellular injury, even in cases of significant accidental overdose.We report the case of a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.