Article
Disruption of diapause induction by TALEN-based gene mutagenesis in relation to a unique neuropeptide signaling pathway in Bombyx.
Scientific reports - 26 Oct 2015
Shiomi Kunihiro, Takasu Yoko, Kunii Masayo, Tsuchiya Ryoma, Mukaida Moeka, Kobayashi Masakazu, Sezutsu Hideki, Ichida Takahama Masatoshi, Mizoguchi Akira
Abstract excerpt
The insect neuropeptide family FXPRLa, which carries the Phe-Xaa-Pro-Arg-Leu-NH2 sequence at the C-terminus, is involved in many physiological processes. Although ligand-receptor interactions in FXPRLa signaling have been examined using in vitro assays, the correlation between these interactions and in vivo physiological function is unclear. Diapause in the silkworm, Bombyx mori, is thought to be elicited by...
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