Article
A miRNA signature in leukocytes from sporadic amyotrophic lateral sclerosis.
Gene - 15 Oct 2012
De Felice Bruna, Guida Marco, Guida Maurizio, Coppola Cinzia, De Mieri Giovanna, Cotrufo Roberto
Abstract excerpt
Amyotrophic lateral sclerosis (ALS) is a progressive and seriously disabling adult-onset neurological disease. Accumulating evidence indicates that various miRNAs, expressed in a spatially and temporally controlled manner in the brain, play a key role in neuronal development. In addition, misregulation of microRNAs contributes to some mental disorders and neurodegeneration diseases. Here, we analyzed the...
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