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Article

Application of retinoic acid improves form and function of tissue engineered corneal construct

3 Jul 2015

Abstract excerpt

Retinoic acid has recently been shown to control the phenotype and extracellular matrix composition of corneal stromal cells cultured in vitro as monolayers. This study set out to investigate the effects of retinoic acid on human corneal keratocytes within a 3D environment. Human corneal keratocytes were encapsulated in collagen gels, which were subsequently compressed under load, and cultured in serum-free media...

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Identifiers

PMID: 26496651
DOI: 10.1080/15476278.2015.1093267

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