Article
An in vitro 3-dimensional Collagen-based Corneal Construct with Innervation Using Human Corneal Cell Lines
6 May 2024
Abstract excerpt
Purpose: To develop a 3-dimensional corneal construct suitable for in vitro studies of disease conditions and therapies. Design: In vitro human corneal constructs were created using chemically crosslinked collagen and chondroitin sulfate extracellular matrix and seeded with 3 human corneal cell types (epithelial, stromal, and endothelial) together with neural cells. The neural cells were derived from hybrid...
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