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Article

The role of HOXB2 and HOXB3 in acute myeloid leukemia.

Biochemical and biophysical research communications - 27 Nov 2015

Lindblad Oscar, Chougule Rohit A, Moharram Sausan A, Kabir Nuzhat N, Sun Jianmin, Kazi Julhash U, Rönnstrand Lars

Abstract excerpt

Acute myeloid leukemia (AML) is a heterogeneous aggressive disease and the most common form of adult leukemia. Mutations in the type III receptor tyrosine kinase FLT3 are found in more than 30% of AML patients. Drugs against FLT3 have been developed for the treatment of AML, but they lack specificity, show poor response and lead to the development of a resistant phenotype upon treatment. Therefore, a deeper...

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Source

Identifiers

PMID: 26482852
DOI: 10.1016/j.bbrc.2015.10.071

Genes

FLT3
HOXB2
HOXB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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