Article
Low indoleamine 2,3-dioxygenase activity in persistent food allergy in children.
Allergy - 1 Feb 2016
Buyuktiryaki B, Sahiner U M, Girgin G, Birben E, Soyer O U, Cavkaytar O, Cetin C, Arik Yilmaz E, Yavuz S T, Kalayci O, Baydar T, Sackesen C
Abstract excerpt
BACKGROUND: Indoleamine 2,3-dioxygenase (IDO), which degrades tryptophan (Trp) to kynurenine (Kyn), has been demonstrated to contribute to modulation of allergic responses. However, the role of IDO in food allergy has not yet been elucidated. METHODS: Serum Trp and Kyn concentrations were analyzed by high-pressure liquid chromatography. Expression of IDO gene was measured by real-time PCR. The levels of...
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