Article
HEALER: homomorphic computation of ExAct Logistic rEgRession for secure rare disease variants analysis in GWAS.
Bioinformatics (Oxford, England) - 15 Jan 2016
Wang Shuang, Zhang Yuchen, Dai Wenrui, Lauter Kristin, Kim Miran, Tang Yuzhe, Xiong Hongkai, Jiang Xiaoqian
Abstract excerpt
MOTIVATION: Genome-wide association studies (GWAS) have been widely used in discovering the association between genotypes and phenotypes. Human genome data contain valuable but highly sensitive information. Unprotected disclosure of such information might put individual's privacy at risk. It is important to protect human genome data. Exact logistic regression is a bias-reduction method based on a penalized...
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