Article
Optimized homomorphic encryption solution for secure genome-wide association studies.
BMC medical genomics - 21 Jul 2020
Blatt Marcelo, Gusev Alexander, Polyakov Yuriy, Rohloff Kurt, Vaikuntanathan Vinod
Abstract excerpt
BACKGROUND: Genome-Wide Association Studies (GWAS) refer to observational studies of a genome-wide set of genetic variants across many individuals to see if any genetic variants are associated with a certain trait. A typical GWAS analysis of a disease phenotype involves iterative logistic regression of a case/control phenotype on a single-neuclotide polymorphism (SNP) with quantitative covariates. GWAS have been...
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