Article
Mechanisms to protect the privacy of families when using the transmission disequilibrium test in genome-wide association studies.
Bioinformatics (Oxford, England) - 1 Dec 2017
Wang Meng, Ji Zhanglong, Wang Shuang, Kim Jihoon, Yang Hai, Jiang Xiaoqian, Ohno-Machado Lucila
Abstract excerpt
MOTIVATION: Inappropriate disclosure of human genomes may put the privacy of study subjects and of their family members at risk. Existing privacy-preserving mechanisms for Genome-Wide Association Studies (GWAS) mainly focus on protecting individual information in case-control studies. Protecting privacy in family-based studies is more difficult. The transmission disequilibrium test (TDT) is a powerful...
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