Article
Differences in Common Genetic Predisposition to Ischemic Stroke by Age and Sex.
Stroke - 1 Nov 2015
Traylor Matthew, Rutten-Jacobs Loes C A, Holliday Elizabeth G, Malik Rainer, Sudlow Cathie, Rothwell Peter M, Maguire Jane M, Koblar Simon A, Bevan Steve, Boncoraglio Giorgio, Dichgans Martin, Levi Chris, Lewis Cathryn M, Markus Hugh S
Abstract excerpt
BACKGROUND AND PURPOSE: Evidence from epidemiological studies points to differences in factors predisposing to stroke by age and sex. Whether these arise because of different genetic influences remained untested. Here, we use data from 4 genome-wide association data sets to study the relationship between genetic influence on stroke with both age and sex. METHODS: Using genomic-relatedness-matrix restricted...
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