Article
Comparative analysis of four disease prediction models of Parkinson's disease.
Molecular and cellular biochemistry - 1 Jan 2016
Kumudini Nadella, Naushad Shaik Mohammad, Alex Stanley Balraj, Niveditha Manoharan, Sharmila Gunasekaran, Kumaraswami Konda, Borghain Rupam, Mridula Rukmini, Kutala Vijay Kumar
Abstract excerpt
Parkinson's disease (PD) is a multi-factorial disorder with high-penetrant mutations accounting for small percentage of PD. Our previous studies demonstrated individual association of genetic variants in folate, xenobiotic, and dopamine metabolic pathways with PD risk. The rational of the study was to develop a risk prediction model for PD using these genetic polymorphisms along with synuclein (SNCA)...
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