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Article

Counteractive functions are encrypted in the residues of CD154.

Human immunology - 1 Sept 2015

Bandyopadhyay Syamdas, Chandel Himanshu Singh, Singh Shailza, Roy Somenath, Krishnasastry M V, Saha Bhaskar

Abstract excerpt

CD40, as a single receptor that binds CD154 (CD40-ligand or CD40L), regulates counteractive effector functions such as production of pro- and anti-inflammatory cytokines. Therefore, we examined whether such dual messages are encrypted in CD40L. As such message encryption was never investigated, we hypothesized that mutation of certain amino acid residues should in principle enhance pro-inflammatory cytokine...

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Share to CD40 Ligand
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26429321
DOI: 10.1016/j.humimm.2015.09.019

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