Article
Influence of dopamine receptor gene polymorphisms on circulating T lymphocytes: A pilot study in healthy subjects.
Human immunology - 1 Oct 2015
Cosentino Marco, Ferrari Marco, Kustrimovic Natasa, Rasini Emanuela, Marino Franca
Abstract excerpt
Dopamine is a key transmitter in the neuroimmune network, acting through five dopaminergic receptors (DR): the D1-like D1 and D5 and the D2-like D2, D3 and D4. Several DR gene variants exist and may affect DR expression and activity. We assessed total lymphocytes, CD3+, CD4+ and CD8+ T lymphocytes in peripheral blood of healthy subjects and their association with selected DR gene variants (DRD1 rs4532 and rs686,...
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