Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Acute stimulation of PBMCs drives switch from dopamine-induced anti- to proinflammatory phenotype of monocytes only in women.

Biology of sex differences - 3 Feb 2025

Fleige Leonie, Capellino Silvia

Abstract excerpt

Several studies report an impact of the neurotransmitter dopamine (DA) on human immune cells, with effects dependent on the immune cell type addressed and their activation status. Another contributing factor appears to be sex, as sex-specific differences in the dopaminergic pathway are described in the neurological context as well as in autoimmune diseases. However, a deeper understanding of these differences in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokines
Share to Dopamine
Share to Inflammation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Leukocytes, Mononuclear

Share to Monocytes

Share to Receptors, Dopamine

Share to Sex Characteristics

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 39901238
DOI: 10.1186/s13293-025-00689-5
PMCID: PMC11789415

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Acute stimulation of PBMCs drives switch from dopamine-induced anti- to proinflammatory phenotype of monocytes only in women.PMID 39901238Read ↗

Acute Stimulation of PBMCs Drives Switch from Dopamine-Induced Anti- to proinflammatory Phenotype of Monocytes Only in WomenSemantic proximity Read ↗

Epigenetic Regulation of Inflammation by Dopamine in Primary Human MacrophagesSemantic proximity Read ↗

Dopamine-driven Increase in IL-1β in Myeloid Cells is Mediated by Differential Dopamine Receptor Expression and Exacerbated by HIVSemantic proximity Read ↗

Expression of Dopamine Receptors in Immune Regulatory CellsSemantic proximity Read ↗

Divergent effects of norepinephrine, dopamine and substance P on the activation, differentiation and effector functions of human cytotoxic T lymphocytesSemantic proximity Read ↗

Dopamine receptor agonist cabergoline promotes immunogenic phenotype in human monocyte-derived dendritic cells.Semantic proximity Read ↗

ScRNA-seq reveals the chronic methamphetamine-induced immunosuppression in murine PBMC with involvement of dopamine receptor D1Semantic proximity Read ↗

Influence of dopamine receptor gene polymorphisms on circulating T lymphocytes: A pilot study in healthy subjects.Semantic proximity Read ↗

Sex-based differences in the activation of peripheral blood monocytes in early Parkinson diseaseSemantic proximity Read ↗

Changes in CD163+, CD11b+, and CCR2+ peripheral monocytes relate to Parkinson’s disease and cognitionSemantic proximity Read ↗

Dopamine up-regulates Th17 phenotype from individuals with generalized anxiety disorder.Semantic proximity Read ↗

TLR9-activated B cells improve their regulatory function by endogenously produced catecholaminesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.