Article
Mechano-logical model of C. elegans germ line suggests feedback on the cell cycle
1 Jan 2015
Abstract excerpt
The Caenorhabditis elegans germ line is an outstanding model system in which to study the control of cell division and differentiation. Although many of the molecules that regulate germ cell proliferation and fate decisions have been identified, how these signals interact with cellular dynamics and physical forces within the gonad remains poorly understood. We therefore developed a dynamic, 3D in silico model of...
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