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Article

Identification of novel hereditary cancer genes by whole exome sequencing.

Cancer letters - 28 Dec 2015

Sokolenko Anna P, Suspitsin Evgeny N, Kuligina Ekatherina Sh, Bizin Ilya V, Frishman Dmitrij, Imyanitov Evgeny N

Abstract excerpt

Whole exome sequencing (WES) provides a powerful tool for medical genetic research. Several dozens of WES studies involving patients with hereditary cancer syndromes have already been reported. WES led to breakthrough in understanding of the genetic basis of some exceptionally rare syndromes; for example, identification of germ-line SMARCA4 mutations in patients with ovarian hypercalcemic small cell carcinomas...

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Source

Identifiers

PMID: 26427841
DOI: 10.1016/j.canlet.2015.09.014

Genes

SMARCA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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