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Article

Amygdala network dysfunction in late-life depression phenotypes: Relationships with symptom dimensions.

Journal of psychiatric research - 1 Nov 2015

Li Wenjun, Ward B Douglas, Xie Chunming, Jones Jennifer L, Antuono Piero G, Li Shi-Jiang, Goveas Joseph S

Abstract excerpt

The amygdala, a crucial hub of the emotional processing neural system, has been implicated in late-life depression (LLD) pathophysiology. However, the overlapping and diverging amygdala network function abnormalities underlying two clinical LLD phenotypes (i.e., LLD alone and LLD with mild cognitive impairment [LLD-MCI]) are unknown. The aim of this study is to investigate the amygdala functional connectivity...

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Source

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Identifiers

PMID: 26424431
DOI: 10.1016/j.jpsychires.2015.09.002
PMCID: PMC4605880

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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