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Novel Type XII Staphylococcal Cassette Chromosome mec Harboring a New Cassette Chromosome Recombinase, CcrC2.

Antimicrobial agents and chemotherapy - 1 Dec 2015

Wu Zhaowei, Li Fan, Liu Dongliang, Xue Huping, Zhao Xin

Abstract excerpt

Excision and integration of staphylococcal cassette chromosome mec (SCCmec) are mediated by cassette chromosome recombinases (Ccr), which play a crucial role in the worldwide spread of methicillin resistance in staphylococci. We report a novel ccr gene, ccrC2, in the SCCmec of a Staphylococcus aureus isolate, BA01611, which showed 62.6% to 69.4% sequence identities to all published ccrC1 sequences. A further...

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Identifiers

PMID: 26416872
DOI: 10.1128/AAC.01692-15
PMCID: PMC4649182

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