Article
Novel mobile variants of staphylococcal cassette chromosome mec in Staphylococcus aureus.
Antimicrobial agents and chemotherapy - 1 Jun 2006
Jansen W T M, Beitsma M M, Koeman C J, van Wamel W J B, Verhoef J, Fluit A C
Abstract excerpt
Staphylococcus aureus staphylococcal cassette chromosome mec type IV (SSCmec IV) is associated with virulent community-acquired methicillin-resistant Staphylococcus aureus (MRSA) and frequent horizontal transfer among staphylococci. To gain insight into the mechanism of transfer, we studied the ccrA/B type 2 recombinase-mediated excision of SCCmec IV (n = 5 strains) and SCCmec II (n = 2). In SCCmec IV- but not...
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