Article
Shared reservoir of ccrB gene sequences between coagulase-negative staphylococci and methicillin-resistant Staphylococcus aureus.
The Journal of antimicrobial chemotherapy - 1 Aug 2013
Fluit Ad C, Carpaij Neeltje, Majoor Eline A M, Bonten Marc J M, Willems Rob J L
Abstract excerpt
OBJECTIVES: Methicillin resistance in Staphylococcus aureus and coagulase-negative staphylococci (CoNS) is caused by expression of the low-affinity penicillin-binding protein (PBP) 2a encoded by the mecA gene. This gene is carried on the staphylococcal cassette chromosome mec (SCCmec) of which several types and subtypes have been described. CoNS and S. aureus share SCCmec types and it has been suggested that CoNS...
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