Article
Regulation of Adaptive NK Cells and CD8 T Cells by HLA-C Correlates with Allogeneic Hematopoietic Cell Transplantation and with Cytomegalovirus Reactivation.
Journal of immunology (Baltimore, Md. : 1950) - 1 Nov 2015
Horowitz Amir, Guethlein Lisbeth A, Nemat-Gorgani Neda, Norman Paul J, Cooley Sarah, Miller Jeffrey S, Parham Peter
Abstract excerpt
Mass cytometry was used to investigate the effect of CMV reactivation on lymphocyte reconstitution in hematopoietic cell transplant patients. For eight transplant recipients (four CMV negative and four CMV positive), we studied PBMCs obtained 6 mo after unrelated donor hematopoietic cell transplantation (HCT). Forty cell-surface markers, distinguishing all major leukocyte populations in PBMC, were analyzed with...
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