Article
Genetic polymorphism and evolutionary differentiation of Eastern Chinese Han: a comprehensive and comparative analysis on KIRs.
Scientific reports - 16 Feb 2017
Yin Caiyong, Hu Li, Huang Huijie, Yu Yanfang, Li Zheng, Ji Qiang, Kong Xiaochao, Wang Zhongqun, Yan Jinchuan, Yan Jiangwei, Zhu Bofeng, Chen Feng
Abstract excerpt
Killer cell immunoglobulin-like receptor genes, namely KIRs, cluster together within the 160 kb genomic DNA region. In this study, we used PCR-SSP approach and successfully identified the genotype of 17 KIR genes in 123 independent healthy donors residing in the Jiangsu province, China. All individuals were positive at the 7 genes. The observed carrier gene frequencies (OFs) of remaining 10 KIRs ranged from...
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