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Article

Allelic polymorphism of KIR2DL2/2DL3 in a southern Chinese population.

Tissue antigens - 1 Nov 2015

Zhen J, He L, Xu Y, Zhao J, Yu Q, Zou H, Sun G, Deng Z

Abstract excerpt

KIR2DL2 and KIR2DL3 segregate as alleles of the same killer cell immunoglobulin-like receptor (KIR) gene locus. They have been associated with viral infectious diseases and certain cancers and their allelic information may help to better comprehend mechanisms. The allelic polymorphism of KIR2DL2/2DL3 has been shown to influence their binding specificity and affinity to the HLA-C1 ligands. The present study aims...

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PMID: 26423800
DOI: 10.1111/tan.12681

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