Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Combined "Infiltrating Astrocytoma/Pleomorphic Xanthoastrocytoma" Harboring IDH1 R132H and BRAF V600E Mutations.

The American journal of surgical pathology - 1 Feb 2016

Yamada Seiji, Kipp Benjamin R, Voss Jesse S, Giannini Caterina, Raghunathan Aditya

Abstract excerpt

Pleomorphic xanthoastrocytoma (PXA) has rarely been reported in combination with infiltrating glioma, historically interpreted as a "collision tumor." Isocitrate dehydrogenase 1 (IDH1) and BRAF V600E mutations are usually not concurrent. The former is typical of adult infiltrating gliomas, and the latter is identified in a variety of primary central nervous system neoplasms, including PXA, ganglioglioma,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Astrocytoma
Share to Brain Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunohistochemistry

Share to Isocitrate Dehydrogenase

Share to Magnetic Resonance Imaging

Share to Neoplasm Invasiveness

Share to Proto-Oncogene Proteins B-raf

Share to Xanthomatosis

Source

Identifiers

PMID: 26414224
DOI: 10.1097/PAS.0000000000000515

Genes

BRAF
IDH1
ATRX

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Combined "Infiltrating Astrocytoma/Pleomorphic Xanthoastrocytoma" Harboring IDH1 R132H and BRAF V600E Mutations.PMID 26414224Read ↗

Combined Diffuse Astrocytoma and Pleomorphic Xanthoastrocytoma Grade III Sharing IDH1 R132H Mutation.Semantic proximity Read ↗

Oligodendroglioma showing pleomorphic xanthoastrocytoma-like perivascular microlesion: With IDH1, TERT promoter mutation and 1p/19q codeletion detected in both components.Semantic proximity Read ↗

Cerebellar pleomorphic xanthoastrocytoma in a patient with neurofibromatosis type 1: a case report and literature review.Semantic proximity Read ↗

The evolution of pleomorphic xanthoastrocytoma: from genesis to molecular alterations and mimics.Semantic proximity Read ↗

Anaplastic PXA in adults: case series with clinicopathologic and molecular features.Semantic proximity Read ↗

Pleomorphic xanthoastrocytoma: report of two cases with unconventional clinical presentations.Semantic proximity Read ↗

Targeted Next-Generation Sequencing Reveals Divergent Clonal Evolution in Components of Composite Pleomorphic Xanthoastrocytoma-Ganglioglioma.Semantic proximity Read ↗

BRAF V600E-mutated diffuse glioma in an adult patient: a case report and review.Semantic proximity Read ↗

Epithelioid GBMs show a high percentage of BRAF V600E mutation.Semantic proximity Read ↗

Impact of WHO 2016 update of brain tumor classification, molecular markers and clinical outcomes in pleomorphic xanthoastrocytoma.Semantic proximity Read ↗

Alternative lengthening of telomeres, ATRX loss and H3-K27M mutations in histologically defined pilocytic astrocytoma with anaplasia.Semantic proximity Read ↗

Combined pleomorphic xanthoastrocytoma-ganglioglioma with BRAF V600E mutation: case report.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.