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Article

A letter on ABCB4 from Iceland: On the highway to liver disease.

Clinics and research in hepatology and gastroenterology - 1 Dec 2015

Lammert F, Hochrath K

Abstract excerpt

Large-scale whole-genome sequencing of the Icelandic population identified an association between several mutations of ABCB4 encoding the hepatobiliary phosphatiylcholine floppase with liver diseases and function in the general population. Whereas rare mutations of this transporter were known to cause progressive familial intrahepatic cholestasis, the genome-wide association studies in Iceland find the common...

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Share to ATP Binding Cassette Transporter, Subfamily B
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Identifiers

PMID: 26410236
DOI: 10.1016/j.clinre.2015.08.004

Genes

ABCB4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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