Article
Hierarchical Rules for Read-Across and In Silico Models of Mutagenicity.
Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews - 1 Jan 2015
Benfenati Emilio, Manganelli Serena, Giordano Sabrina, Raitano Giuseppa, Manganaro Alberto
Abstract excerpt
A broad set of rules has been implemented within the ToxRead software for read-across of chemicals for bacterial mutagenicity. These rules were obtained by manually analyzing more than 6000 chemicals and the associated chemical classes. A hierarchy of rules was established to identify those most specifically relating to the target compounds, linked in sequence to the other, more generic ones, which may match with...
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