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Article

RAF Kinase Inhibitor Protein in Myeloid Leukemogenesis.

International journal of molecular sciences - 16 Nov 2019

Zebisch Armin, Caraffini Veronica, Sill Heinz

Abstract excerpt

RAF kinase inhibitor protein (RKIP) is an essential regulator of intracellular signaling. A somatic loss of RKIP expression is a frequent event in solid human cancers, and a role of RKIP as metastasis-suppressor is widely accepted nowadays. Recently, RKIP loss has been described in acute myeloid leukemia (AML) and a series of other myeloid neoplasias (MNs). Functional in vitro and in vivo experiments revealed...

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Identifiers

PMID: 31744053
DOI: 10.3390/ijms20225756
PMCID: PMC6888401

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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