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Article

Modeling the Aggregation Propensity and Toxicity of Amyloid-β Variants.

Journal of Alzheimer's disease : JAD - 1 Jan 2015

Tiwari Manish K, Kepp Kasper P

Abstract excerpt

Protein aggregation is a hallmark of many neurodegenerative disorders. Alzheimer's disease (AD) is directly linked to deposits of amyloid-β (Aβ) derived from the amyloid-β protein precursor (AβPP), and multiple experimental studies have investigated the aggregation behavior of these amyloids. The present paper reports modeling of the aggregation propensities and cell toxicities of genetic variants of Aβ known to...

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Identifiers

PMID: 26402770
DOI: 10.3233/JAD-150046

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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