Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differential Toxicity of Nuclear RNA Foci versus Dipeptide Repeat Proteins in a Drosophila Model of C9ORF72 FTD/ALS

1 Sept 2015

Abstract excerpt

No abstract is available from the source.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyotrophic Lateral Sclerosis Research
Share to Biochemical Acid Research Studies
Share to Prion Diseases and Protein Misfolding

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 26402604
DOI: 10.1016/j.neuron.2015.09.015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differential Toxicity of Nuclear RNA Foci versus Dipeptide Repeat Proteins in a Drosophila Model of C9ORF72 FTD/ALSPMID 26402604Read ↗

RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense InterventionSemantic proximity Read ↗

Antisense Proline-Arginine RAN Dipeptides Linked to C9ORF72-ALS/FTD Form Toxic Nuclear Aggregates that Initiate In Vitro and In Vivo Neuronal DeathSemantic proximity Read ↗

DDX3X overexpression decreases dipeptide repeat proteins in a mouse model of C9ORF72-ALS/FTDSemantic proximity Read ↗

Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTDSemantic proximity Read ↗

Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALSSemantic proximity Read ↗

ADAR2 mislocalization and widespread RNA editing aberrations in C9orf72-mediated ALS/FTDSemantic proximity Read ↗

FTD/ALS-associated poly(GR) protein impairs the Notch pathway and is recruited by poly(GA) into cytoplasmic inclusionsSemantic proximity Read ↗

Sense and antisense RNA are not toxic in Drosophila models of C9orf72-associated ALS/FTDSemantic proximity Read ↗

Therapeutic reduction of GGGGCC repeat RNA levels by hnRNPA3 suppresses neurodegeneration in Drosophila models of C9orf72 -linked ALS/FTDSemantic proximity Read ↗

Insights into C9ORF72-Related ALS/FTD from Drosophila and iPSC ModelsSemantic proximity Read ↗

Unraveling the Role of RNA Mediated Toxicity of C9orf72 Repeats in C9-FTD/ALSSemantic proximity Read ↗

Nucleocytoplasmic Proteomic Analysis Uncovers eRF1 and Nonsense-Mediated Decay as Modifiers of ALS/FTD C9orf72 ToxicitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.