Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multiple Spontaneous Cerebral Microbleeds and Leukoencephalopathy in PSEN1-Associated Familial Alzheimer's Disease: Mirror of Cerebral Amyloid Angiopathy?

Journal of Alzheimer's disease : JAD - 1 Jan 2015

Floris Gianluca, Di Stefano Francesca, Cherchi Maria Valeria, Costa Gianna, Marrosu Francesco, Marrosu Maria Giovanna

Abstract excerpt

Cerebral microbleeds (CMB) might reflect specific underlying vascular pathologies like cerebral amyloid angiopathy (CAA). In the present study we report the gradient-echo MRI pattern of two siblings with P284S PSEN1 mutation. T2* gradient-echo images of the two subjects demonstrated multiple microbleeds in lobar regions. The role and causes of CMB in sporadic Alzheimer's disease (AD) patients have not been...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to Brain

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cerebral Amyloid Angiopathy

Share to Leukoencephalopathies

Share to Magnetic Resonance Imaging

Share to Pedigree

Share to Presenilin-1

Share to Siblings

Source

Identifiers

PMID: 26401689
DOI: 10.3233/JAD-150165

Genes

PSEN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multiple Spontaneous Cerebral Microbleeds and Leukoencephalopathy in PSEN1-Associated Familial Alzheimer's Disease: Mirror of Cerebral Amyloid Angiopathy?PMID 26401689Read ↗

Cerebral Microbleeds as a Biomarker in Alzheimer’S Disease? A Review in The FieldSemantic proximity Read ↗

Pathologically Confirmed Cerebral Amyloid Angiopathy with No Radiological Sign in a Patient with Early Onset Alzheimer's Disease.Semantic proximity Read ↗

Brain hemorrhages in cerebral amyloid angiopathy.Semantic proximity Read ↗

Prevalence and risk factors of cerebral microbleeds: the Rotterdam Scan Study.Semantic proximity Read ↗

Cerebral Amyloid Angiopathy Burden and Cerebral Microbleeds: Pathological Evidence for Distinct Phenotypes.Semantic proximity Read ↗

[Clinical relevance of cerebral microbleeds--update].Semantic proximity Read ↗

Fatal Iatrogenic Cerebral Amyloid-Related Encephalitis in a patient treated with lecanemab for Alzheimer’s disease: neuroimaging and neuropathologySemantic proximity Read ↗

Visualization of microbleeds with optical histology in mouse model of cerebral amyloid angiopathy.Semantic proximity Read ↗

Apolipoprotein E genotype influences spatial distribution of cerebral microbleeds.Semantic proximity Read ↗

White matter hyperintensities and the mediating role of cerebral amyloid angiopathy in dominantly-inherited Alzheimer's disease.Semantic proximity Read ↗

The cerebral beta-amyloid angiopathies: hereditary and sporadic.Semantic proximity Read ↗

Microbleeds in hereditary cerebral hemorrhage with amyloidosis-Dutch type.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.