Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification and Validation of Ubiquitin-Specific Proteases as a Novel Prognostic Signature for Hepatocellular Carcinoma

25 Feb 2021

Abstract excerpt

PURPOSE: Ubiquitin-specific proteases (USPs), as a sub-family of deubiquitinating enzymes (DUBs), are responsible for the elimination of ubiquitin-triggered modification. USPs are recently correlated with various malignancies. However, the expression features and clinical significance of USPs have not been systematically investigated in hepatocellular carcinoma (HCC). METHODS: Genomic alterations and expression...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Clusterin in disease pathology
Share to Histone Deacetylase Inhibitors Research
Share to Ubiquitin and proteasome pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33718205
DOI: 10.3389/fonc.2021.629327

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification and Validation of Ubiquitin-Specific Proteases as a Novel Prognostic Signature for Hepatocellular CarcinomaPMID 33718205Read ↗

Gene Signature and Prognostic Value of Ubiquitin-Specific Proteases Members in Hepatocellular Carcinoma and Explored the Immunological Role of USP36Semantic proximity Read ↗

Ubiquitin-specific protease 11 serves as a marker of poor prognosis and promotes metastasis in hepatocellular carcinomaSemantic proximity Read ↗

Comprehensive analysis of ubiquitin‐specific protease 1 reveals its importance in hepatocellular carcinomaSemantic proximity Read ↗

USP39 promotes tumorigenesis by stabilizing and deubiquitinating SP1 protein in hepatocellular carcinomaSemantic proximity Read ↗

Ubiquitin-specific peptidase 10, a deubiquitinating enzyme: Assessing its role in tumor prognosis and immune responseSemantic proximity Read ↗

The deubiquitinase USP21 stabilizes MEK2 to promote tumor growthSemantic proximity Read ↗

The expression of ubiquitin‐specific peptidase 8 and its prognostic role in patients with breast cancerSemantic proximity Read ↗

Identification and Validation of a Necroptosis-related Gene based Prognostic Signature for Patients with Hepatocellular CarcinomaSemantic proximity Read ↗

Emerging Role of Ubiquitin-Specific Protease 19 in Oncogenesis and Cancer DevelopmentSemantic proximity Read ↗

Emerging potential of ubiquitin-specific proteases and ubiquitin-specific proteases inhibitors in breast cancer treatmentSemantic proximity Read ↗

Emerging Potential of Therapeutic Targeting of Ubiquitin-Specific Proteases in the Treatment of CancerSemantic proximity Read ↗

A ubiquitin-related gene signature for predicting prognosis and constructing molecular subtypes in osteosarcomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.