Genomic approaches to studying human-specific developmental traits.

Abstract excerpt

Changes in developmental regulatory programs drive both disease and phenotypic differences among species. Linking human-specific traits to alterations in development is challenging, because we have lacked the tools to assay and manipulate regulatory networks in human and primate embryonic cells. This field was transformed by the sequencing of hundreds of genomes--human and non-human--that can be compared to...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Gene Expression Regulation, Developmental
• Share to Gene Regulatory Networks
• Share to Genome, Human