Article
Association between functional PSMD10 Rs111638916 variant regulated by MiR-505 and gastric cancer risk in a Chinese population.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2015
Liu Yong, Xu Jianzhong, Jiang Min, Ni Lingna, Chen Yun, Ling Yang
Abstract excerpt
BACKGROUND/AIMS: Gankyrin is an oncoprotein involved in regulating the cell cycle through protein-protein interactions with cyclin-dependent kinase 4 and p53. However, its association with gastric cancer (GC) risk has not yet been determined. In this study, we investigated micro RNA (miRNA)-associated single nucleotide polymorphisms (SNPs) in the 3'-untranslated region (UTR) of the gankyrin gene PSMD10 to clarify...
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