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Article

Maspin genetically and functionally associates with gastric cancer by regulating cell cycle progression.

Carcinogenesis - 1 Dec 2012

Kim Minjin, Ju Hyoungseok, Lim Byungho, Kang Changwon

Abstract excerpt

Human SERPINB5, commonly known as maspin, has diverse functions as a tumor suppressor. In this study, we discovered that maspin has a novel role in cell cycle control, and common variants were discovered to be associated with gastric cancer. The genotypes of 836 unrelated Korean participants (including 430 with gastric cancer) were examined for 12 tag single-nucleotide polymorphisms (SNPs) and imputed for 178...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22962304
DOI: 10.1093/carcin/bgs280

Genes

CDK1
SERPINB5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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