Article
The future of CFTR modulating therapies for cystic fibrosis.
Current opinion in pulmonary medicine - 1 Nov 2015
Davies Jane C
Abstract excerpt
PURPOSE OF REVIEW: Huge progress has been made over the last few years in the field of small molecule therapies targeting cystic fibrosis transmembrane conductance regulator (CFTR), the protein defective in patients with cystic fibrosis. This review describes the progress and areas of future research. RECENT FINDINGS: Ivacaftor is the first drug of its kind to be licensed for clinical use in patients with a...
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