Article
The phenotypic fate and functional role for bone marrow-derived stem cells in liver fibrosis.
Journal of hepatology - 1 Apr 2012
Kisseleva Tatiana, Brenner David A
Abstract excerpt
Liver fibrosis is an outcome of chronic liver injury of any etiology. It is manifested by extensive deposition of extracellular matrix (ECM) proteins that produce a fibrous scar in the injured liver. Bone marrow (BM) cells may play an important role in pathogenesis and resolution of liver fibrosis. BM cells contribute to the inflammatory response by TGF-β1 secretion and activation of liver resident...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
