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Article

Predicting Progression of ABCA4-Associated Retinal Degenerations Based on Longitudinal Measurements of the Leading Disease Front.

Investigative ophthalmology & visual science - 1 Sept 2015

Cideciyan Artur V, Swider Malgorzata, Schwartz Sharon B, Stone Edwin M, Jacobson Samuel G

Abstract excerpt

PURPOSE: To evaluate the progression of the earliest stage of disease in ABCA4-associated retinal degenerations (RDs). METHODS: Near-infrared excited reduced-illuminance autofluorescence imaging was acquired across the retina up to 80 degrees eccentricity in 44 patients with two ABCA4 alleles. The eccentricity of the leading disease front (LDF) corresponding to the earliest stage of disease was measured along the...

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Source

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Identifiers

PMID: 26377081
DOI: 10.1167/iovs.15-17698
PMCID: PMC4572941

Genes

ABCA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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