Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inner and outer retinal changes in retinal degenerations associated with ABCA4 mutations.

Investigative ophthalmology & visual science - 20 Mar 2014

Huang Wei Chieh, Cideciyan Artur V, Roman Alejandro J, Sumaroka Alexander, Sheplock Rebecca, Schwartz Sharon B, Stone Edwin M, Jacobson Samuel G

Abstract excerpt

PURPOSE: To investigate in vivo inner and outer retinal microstructure and effects of structural abnormalities on visual function in patients with retinal degeneration caused by ABCA4 mutations (ABCA4-RD). METHODS: Patients with ABCA4-RD (n = 45; age range, 9-71 years) were studied by spectral-domain optical coherence tomography (OCT) scans extending from the fovea to 30° eccentricity along horizontal and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to ATP-Binding Cassette Transporters

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

Share to Retinal Degeneration

Share to Tomography, Optical Coherence

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 24550365
DOI: 10.1167/iovs.13-13768
PMCID: PMC3968929

Genes

ABCA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inner and outer retinal changes in retinal degenerations associated with ABCA4 mutations.PMID 24550365Read ↗

Photoreceptor degeneration in ABCA4-associated retinopathy and its genetic correlatesSemantic proximity Read ↗

Characterization of the Subclinical Perilesional Zone in the Macula of Early-Stage ABCA4 DiseaseSemantic proximity Read ↗

Retinal Structure in RPE65-Associated Retinal Dystrophy.Semantic proximity Read ↗

Investigation of Structural Alterations in Inherited Retinal Diseases: A Quantitative SD-OCT-Analysis of Retinal Layer Thicknesses in Light of Underlying Genetic MutationsSemantic proximity Read ↗

Shared Features in Retinal Disorders With Involvement of Retinal Pigment Epithelium.Semantic proximity Read ↗

Retinal laminar architecture in human retinitis pigmentosa caused by Rhodopsin gene mutations.Semantic proximity Read ↗

Early Patterns of Macular Degeneration in ABCA4-Associated Retinopathy.Semantic proximity Read ↗

ABCA4-associated retinal degenerations spare structure and function of the human parapapillary retina.Semantic proximity Read ↗

PHOTORECEPTOR INNER SEGMENT MORPHOLOGY IN BEST VITELLIFORM MACULAR DYSTROPHYSemantic proximity Read ↗

Spectral domain optical coherence tomography and adaptive optics: imaging photoreceptor layer morphology to interpret preclinical phenotypes.Semantic proximity Read ↗

Retinal remodeling triggered by photoreceptor degenerations.Semantic proximity Read ↗

Relating Retinal Morphology and Function in Aging and Early to Intermediate Age-related Macular Degeneration Subjects.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.