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Article

Analysis of the association between polymorphisms in MMP2, MMP3, MMP9, MMP20, TIMP1, and TIMP2 genes with white spot lesions and early childhood caries.

International journal of paediatric dentistry - 1 Jul 2016

Antunes Lívia Azeredo, Antunes Leonardo Santos, Küchler Erika Calvano, Lopes Ludiana Barbosa, Moura Alex, Bigonha Rhyan Silva, Abreu Fernanda Volpe, Granjeiro José Mauro, de Amorim Lidia Maria da Fonte, Paixão Izabel Christina N P

Abstract excerpt

BACKGROUND: Matrix metalloproteinases and their inhibitors might be involved in enamel formation. AIM: This study aimed to evaluate the association between polymorphisms in MMP2, MMP3, MMP9, MMP20, TIMP1, and TIMP2 with white spot lesions (WSL) and early childhood caries (ECC). DESIGN: A cross-sectional study was performed on 786 children aged from 2 to 6 years in Brazil. After clinical evaluation, they were...

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Source

Identifiers

PMID: 26371789
DOI: 10.1111/ipd.12202

Genes

MMP20
MMP9
MMP2
MMP3
TIMP1
TIMP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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