Association of single nucleotide polymorphisms of enamelin, tuftelin1, and matrix metalloproteinase 20 genes in South Indian children with early childhood caries: A case-control study.

Abstract excerpt

INTRODUCTION: Early childhood caries (ECC) results from a complex interplay of genetic and environmental factors. Polymorphisms of enamel formation genes may alter the susceptibility to ECC. AIM: The primary objective of this study is to analyze the association between rs12640848 of the ENAM gene, rs1376729959 of the TUFT1 gene, and rs1784418 of the MMP20 gene with ECC. MATERIALS AND METHODS: This case-control...