Article
cDNA sequence of the horse (Equus caballus) LAMA3 gene and characterization of two intronic SNP markers.
DNA sequence : the journal of DNA sequencing and mapping - 1 Dec 2005
Milenkovic Dragan, Mata Xavier, Chadi Sead, Guérin Gérard
Abstract excerpt
Laminins are large heterotrimeric basement membrane glycoproteins composed of alpha, beta and gamma chains. The Laminin 5 isoform has an alpha3beta3gamma2 composition and is essential for the adhesion of basal keratinocytes to the underlying epithelial basement membrane where it is mainly located. Mutations in the genes coding for the 3 chains have been associated with a severe skin blistering disease, Herlitz's...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
